Evidence Tracker

Early treatment is a changing futures for young people facing psychosis — but don’t take our word for it!  Take a deeper dive into the science behind early intervention with this short list of notable research from the 2000s.


Early Psychosis Treatment Results


Cost-Effectiveness of Comprehensive, Integrated Care for First Episode Psychosis in the NIMH RAISE Early Treatment Program

Continued versus discontinued cannabis use in patients with psychosis: a systematic review and meta-analysis

Treatment patterns and short-term outcomes in an early intervention youth mental health service

Obstacles to care in first-episode psychosis patients with a long duration of untreated psychosis


Comprehensive Versus Usual Community Care for First-Episode Psychosis: 2-Year Outcomes From the NIMH RAISE Early Treatment Program

Additional RAISE research

First-Episode Services for Psychotic Disorders in the U.S. Public Sector: A Pragmatic Randomized Controlled Trial (STEP Program)

Early Intervention in Psychosis: Obvious, Effective, Overdue

10-year outcome study of an early intervention program for psychosis compared with standard care service


How successful are first episode programs? A review of the evidence for specialised assertive early intervention


Preventing a first episode of psychosis: Meta-analysis of randomised controlled prevention trials of 12 month and medium-term follow-ups

The psychosis high-risk state: A comprehensive state-of-the-art review


Predicting psychosis: A meta-analysis of evidence

Long-term follow-up of the TIPS early detection in psychosis study: effects on 10-year outcome

Providing care to young people with emerging risk of psychosis: Balancing potential risks and benefits


Review: early intervention services can be clinically beneficial for people with early psychosis

Is Early Intervention in Psychosis Cost-Effective Over the Long Term?


Early intervention services, cognitive-behavioural therapy and family intervention in early psychosis: systematic review

Promoting recovery in early psychosis: A practice manual

Feasibility of Implementing Cognitive Behavioral Therapy for Psychosis on Assertive Community Treatment Teams: A Controlled Pilot Study


The recognition and management of early psychosis: A preventive approach, (2nd ed)

Intervention in individuals at ultra high risk for psychosis: A review and future directions


The Key to Reducing Duration of Untreated First Psychosis: Information Campaigns (TIPS study)

Early intervention in psychosis: concepts, evidence and future directions

Working with People at High Risk of Developing Psychosis: A Treatment Handbook


The prevention of schizophrenia

Lifetime Prevalence of Psychotic and Bipolar I Disorders in a General Population


Clinical staging of psychiatric disorders: a heuristic framework for choosing earlier, safer and more effective interventions


Early Intervention and recovery for young people with early psychosis: consensus statement

Association between duration of untreated psychosis and outcome in cohorts of first-episode patients: A systematic review

Early intervention in psychotic disorders: Beyond debate to solving problems


Implementing Early Intervention in Psychosis: A Guide to Establishing Early Psychosis Services

The recognition and optimal management of early psychosis: An evidence-based reform


Supported Employment & Education


Supported Employment Over the Long Term

Long-Term Effectiveness of Supported Employment: Five-Year Follow-up of a Randomized Controlled Trial

From Effectiveness to Sustainability: Life and treatment goals of individuals hospitalized for first-episode nonaffective psychosis


To love and to work: the next major mental health reform goals


Early Intervention Guidelines


Psychosis and schizophrenia in adults: prevention and management


Psychosis and schizophrenia in children and young people: recognition and management


Early Psychosis Guidelines Writing Group, Australian Clinical Guidelines for Early Psychosis, 2nd edition


Schizophrenia. Australian Treatment Guide for Consumers and Carers


International Early Psychosis Association: International clinical practice guidelines for early psychosis

Royal Australian and New Zealand College of Psychiatrists clinical practice guidelines for the treatment of schizophrenia and related disorders


Emerging Treatments


Know of a landmark piece of research you think belongs here?  Shoot us a note.

The nature of published scientific research is largely subscription-based. We’ve attempted to post open source links where available.

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